8SW3

BG505 GT1.1 SOSIP in complex with NHP Fabs 12C11 and RM20A3

This is a non-PDB format compatible entry.

Summary for 8SW3

• Entry DOI: 10.2210/pdb8sw3/pdb
• EMDB information: 40796
• Descriptor: BG505 GT1.1 SOSIP gp120, RM20A3 heavy chain variable region, RM20A3 light chain variable region, ... (9 entities in total)
• Functional Keywords: germline targeting, hiv-1 env, neutralizing antibody, non-human primate antibody, cd4 binding site, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 18
• Total formula weight: 389037.56

Authors

Zhang, S.,Torres, J.L.,Ozorowski, G.,Ward, A.B. (deposition date: 2023-05-17, release date: 2024-09-11, Last modification date: 2024-10-09)

• Primary citation: Caniels, T.G.,Medina-Ramirez, M.,Zhang, S.,Kratochvil, S.,Xian, Y.,Koo, J.H.,Derking, R.,Samsel, J.,van Schooten, J.,Pecetta, S.,Lamperti, E.,Yuan, M.,Carrasco, M.R.,Del Moral Sanchez, I.,Allen, J.D.,Bouhuijs, J.H.,Yasmeen, A.,Ketas, T.J.,Snitselaar, J.L.,Bijl, T.P.L.,Martin, I.C.,Torres, J.L.,Cupo, A.,Shirreff, L.,Rogers, K.,Mason, R.D.,Roederer, M.,Greene, K.M.,Gao, H.,Silva, C.M.,Baken, I.J.L.,Tian, M.,Alt, F.W.,Pulendran, B.,Seaman, M.S.,Crispin, M.,van Gils, M.J.,Montefiori, D.C.,McDermott, A.B.,Villinger, F.J.,Koup, R.A.,Moore, J.P.,Klasse, P.J.,Ozorowski, G.,Batista, F.D.,Wilson, I.A.,Ward, A.B.,Sanders, R.W.; Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.; Sci Immunol, 9:eadk9550-eadk9550, 2024; PubMed: 39213338; DOI: 10.1126/sciimmunol.adk9550

Experimental method

ELECTRON MICROSCOPY (2.8 Å)