8STX

Crystal structure of the F337A mutation of Trypanosoma cruzi glucokinase in the apo form (open conformation)

8STX の概要

• エントリーDOI: 10.2210/pdb8stx/pdb
• 分子名称: Glucokinase (2 entities in total)
• 機能のキーワード: glucokinase, transferase, mutation
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84301.11

構造登録者

Abiskaroon, B.,Carey, S.M.,D'Antonio, E.L.,Chruszcz, M. (登録日: 2023-05-11, 公開日: 2023-05-31, 最終更新日: 2023-12-13)

• 主引用文献: Carey, S.M.,Kearns, S.P.,Millington, M.E.,Buechner, G.S.,Alvarez Jr., B.E.,Daneshian, L.,Abiskaroon, B.,Chruszcz, M.,D'Antonio, E.L.; At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 337.; Biochimie, 218:8-19, 2023; PubMed: 37741546; DOI: 10.1016/j.biochi.2023.09.014

実験手法

X-RAY DIFFRACTION (2.4 Å)