8SPA

Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment

Summary for 8SPA

• Entry DOI: 10.2210/pdb8spa/pdb
• EMDB information: 40677
• Descriptor: Cytoplasmic polyadenylation element-binding protein 3 (1 entity in total)
• Functional Keywords: prion, amyloid, reversible, helical, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 26398.81

Authors

Flores, M.D.,Sawaya, M.R.,Boyer, D.R.,Zink, S.,Fioriti, L.,Rodriguez, J.A. (deposition date: 2023-05-02, release date: 2024-05-08, Last modification date: 2025-05-21)

• Primary citation: Flores, M.D.,Sawaya, M.R.,Boyer, D.R.,Zink, S.,Fioriti, L.,Rodriguez, J.A.; Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)