8SPA

Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment

8SPA の概要

• エントリーDOI: 10.2210/pdb8spa/pdb
• EMDBエントリー: 40677
• 分子名称: Cytoplasmic polyadenylation element-binding protein 3 (1 entity in total)
• 機能のキーワード: prion, amyloid, reversible, helical, protein fibril
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 26398.81

構造登録者

Flores, M.D.,Sawaya, M.R.,Boyer, D.R.,Zink, S.,Fioriti, L.,Rodriguez, J.A. (登録日: 2023-05-02, 公開日: 2024-05-08, 最終更新日: 2025-05-21)

• 主引用文献: Flores, M.D.,Sawaya, M.R.,Boyer, D.R.,Zink, S.,Fioriti, L.,Rodriguez, J.A.; Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation; To Be Published,

実験手法

ELECTRON MICROSCOPY (3 Å)