8SMG

Structure of SPO1 phage Tad2 in complex with 1''-2' gcADPR

8SMG の概要

• エントリーDOI: 10.2210/pdb8smg/pdb
• 分子名称: Gp34.65, (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione (3 entities in total)
• 機能のキーワード: gcadpr, thoeris, anti-phage, viral protein
• 由来する生物種: Okubovirus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 20792.26

構造登録者

Lu, A.,Yirmiya, E.,Leavitt, A.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Amitai, G.,Sorek, R.,Kranzusch, P.J. (登録日: 2023-04-26, 公開日: 2023-11-22, 最終更新日: 2024-01-24)

• 主引用文献: Yirmiya, E.,Leavitt, A.,Lu, A.,Ragucci, A.E.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Kranzusch, P.J.,Amitai, G.,Sorek, R.; Phages overcome bacterial immunity via diverse anti-defence proteins.; Nature, 625:352-359, 2024; PubMed: 37992756; DOI: 10.1038/s41586-023-06869-w

実験手法

X-RAY DIFFRACTION (2.1 Å)