8SLU
Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)
Summary for 8SLU
Entry DOI | 10.2210/pdb8slu/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 5, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ptpn5, step, phosphatase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 32802.21 |
Authors | Ebrahim, A.,Guerrero, L.,Riley, B.T.,Kim, M.,Huang, Q.,Finke, A.D.,Keedy, D.A. (deposition date: 2023-04-24, release date: 2023-06-21, Last modification date: 2023-09-27) |
Primary citation | Guerrero, L.,Ebrahim, A.,Riley, B.T.,Kim, M.,Huang, Q.,Finke, A.D.,Keedy, D.A. Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase. Biorxiv, 2023 Cited by PubMed: 37205580DOI: 10.1101/2023.05.02.538097 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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