8SK1

Bacillus anthracis HPPK in complex with bisubstrate inhibitor HP-73

Summary for 8SK1

• Entry DOI: 10.2210/pdb8sk1/pdb
• Descriptor: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase, 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine (3 entities in total)
• Functional Keywords: bacillus anthracis hppk, bisubstrate inhibitor, hp-73, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Bacillus anthracis
• Total number of polymer chains: 2
• Total formula weight: 41316.83

Authors

Shaw, G.X.,Tropea, J.E.,Shi, G.,Waugh, D.S.,Ji, X. (deposition date: 2023-04-18, release date: 2024-07-03)

• Primary citation: Shaw, G.X.,Tropea, J.E.,Shi, G.,Waugh, D.S.,Ji, X.; Crystal structure of Bacillus anthracis HPPK in complex with bisubstrate inhibitor HP-73; To be published,

Experimental method

X-RAY DIFFRACTION (2 Å)