8SJK
Pembrolizumab Caffeine crystal
Summary for 8SJK
Entry DOI | 10.2210/pdb8sjk/pdb |
Related PRD ID | PRD_900003 |
Descriptor | ANTIBODY LIGHT CHAIN, ANTIBODY HEAVY CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | cancer, antibody, subclasses, igg4, melanoma, nsclc, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 75130.49 |
Authors | Larpent, P.,Codan, L.,Bothe, J.R.,Stueber, D.,Reichert, P.,Fischmann, T.,Su, Y.,Pabit, S.,Gupta, S.,Iuzzolino, L.,Cote, A. (deposition date: 2023-04-18, release date: 2024-04-24) |
Primary citation | Larpent, P.,Codan, L.,Bothe, J.R.,Stueber, D.,Reichert, P.,Fischmann, T.O.,Su, Y.,Pabit, S.,Gupta, S.,Iuzzolino, L.,Cote, A. Smaall angle X-ray scattering as powerful toolsfor phase and crystallinity assessment of monoclonal antibodies crystallites in support of batch crystallization and processing To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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