8SI3

Cryo-EM structure of TRPM7 in GDN detergent in apo state

8SI3 の概要

• エントリーDOI: 10.2210/pdb8si3/pdb
• 関連するPDBエントリー: 8SI2
• EMDBエントリー: 40496 40497
• 分子名称: Transient receptor potential cation channel subfamily M member 7, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, ... (6 entities in total)
• 機能のキーワード: transient receptor potential m family member 7, trp, channel, trpm7, trp channels, membrane protein, magnesium channel
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 630733.15

構造登録者

Nadezhdin, K.D.,Neuberger, A.,Sobolevsky, A.I. (登録日: 2023-04-14, 公開日: 2023-05-17, 最終更新日: 2023-05-24)

• 主引用文献: Nadezhdin, K.D.,Correia, L.,Narangoda, C.,Patel, D.S.,Neuberger, A.,Gudermann, T.,Kurnikova, M.G.,Chubanov, V.,Sobolevsky, A.I.; Structural mechanisms of TRPM7 activation and inhibition.; Nat Commun, 14:2639-2639, 2023; PubMed: 37156763; DOI: 10.1038/s41467-023-38362-3

実験手法

ELECTRON MICROSCOPY (2.61 Å)