8SE1

Structure of Full-length Human Protein Kinase C Beta 2 (PKCBII) in the Inactive Conformation

Summary for 8SE1

• Entry DOI: 10.2210/pdb8se1/pdb
• Descriptor: Protein kinase C beta type, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: protein kinase c beta, kinase, phosphorylation, pkcb, pkc, kinase signalling, prkcb, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 156678.55

Authors

Cong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Jayaraman, S.,Dugan, M.B.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J. (deposition date: 2023-04-07, release date: 2025-08-20)

• Primary citation: Cong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Bhattacharya, S.S.,Jayaraman, S.,Dugan, M.B.,Paluncic, J.,Kuffel, M.J.,Farmakes, J.,Alvey, J.,Wu, X.,Fields, A.P.,Pandey, A.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J.; Molecular Basis of Allosteric Regulation and Pharmaceutical Targeting of Protein Kinase C b; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.32 Å)