8SDH
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.56
Summary for 8SDH
Entry DOI | 10.2210/pdb8sdh/pdb |
Descriptor | Spike protein S1, Neutralizing antibody CC25.56 Heavy Chain, Neutralizing antibody CC25.56 Light Chain, ... (6 entities in total) |
Functional Keywords | sars-cov-2, coronavirus, antibody, immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 6 |
Total formula weight | 139973.39 |
Authors | Yuan, M.,Wilson, I.A. (deposition date: 2023-04-06, release date: 2024-08-07, Last modification date: 2024-09-11) |
Primary citation | Song, G.,Yuan, M.,Liu, H.,Capozzola, T.,Lin, R.N.,Torres, J.L.,He, W.T.,Musharrafieh, R.,Dueker, K.,Zhou, P.,Callaghan, S.,Mishra, N.,Yong, P.,Anzanello, F.,Avillion, G.,Vo, A.L.,Li, X.,Makhdoomi, M.,Feng, Z.,Zhu, X.,Peng, L.,Nemazee, D.,Safonova, Y.,Briney, B.,Ward, A.B.,Burton, D.R.,Wilson, I.A.,Andrabi, R. Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023 Cited by PubMed: 37162858DOI: 10.1101/2023.04.26.538488 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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