8SC8

Structure of PI3KG in complex with MTX-531

8SC8 の概要

• エントリーDOI: 10.2210/pdb8sc8/pdb
• 分子名称: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION, N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide, ... (4 entities in total)
• 機能のキーワード: pi3kg, dual egfr/pi3k inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 111661.36

構造登録者

Whitehead, C.E.,Leopold, J. (登録日: 2023-04-05, 公開日: 2024-06-12)

• 主引用文献: Whitehead, C.E.,Leopold, J.; Structure of PI3KG in complex with MTX-531; To Be Published,

実験手法

X-RAY DIFFRACTION (2.687 Å)