8SBL
Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI
Summary for 8SBL
Entry DOI | 10.2210/pdb8sbl/pdb |
Descriptor | MHC class I antigen, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE (3 entities in total) |
Functional Keywords | major histocompatibility complex (mhc), immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 181730.46 |
Authors | Mallik, L.,Young, M.C.,Sgourakis, N.G. (deposition date: 2023-04-03, release date: 2023-12-06, Last modification date: 2023-12-13) |
Primary citation | Sun, Y.,Florio, T.J.,Gupta, S.,Young, M.C.,Marshall, Q.F.,Garfinkle, S.E.,Papadaki, G.F.,Truong, H.V.,Mycek, E.,Li, P.,Farrel, A.,Church, N.L.,Jabar, S.,Beasley, M.D.,Kiefel, B.R.,Yarmarkovich, M.,Mallik, L.,Maris, J.M.,Sgourakis, N.G. Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8:eadj5792-eadj5792, 2023 Cited by PubMed: 38039376DOI: 10.1126/sciimmunol.adj5792 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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