8SB6

Structure of human BRD2-BD1 bound to a histone H4 acetyl-methyllysine peptide

Summary for 8SB6

Entry DOI	10.2210/pdb8sb6/pdb
Descriptor	Bromodomain containing 2, Histone H4 (3 entities in total)
Functional Keywords	histone peptide protein complex, peptide binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	46862.40
Authors	Connor, L.J.,Ekundayo, B.E.,Lu-Culligan, W.J.,Simon, M.D.,Bleichert, F. (deposition date: 2023-04-02, release date: 2023-07-26, Last modification date: 2023-11-15)
Primary citation	Lu-Culligan, W.J.,Connor, L.J.,Xie, Y.,Ekundayo, B.E.,Rose, B.T.,Machyna, M.,Pintado-Urbanc, A.P.,Zimmer, J.T.,Vock, I.W.,Bhanu, N.V.,King, M.C.,Garcia, B.A.,Bleichert, F.,Simon, M.D. Acetyl-methyllysine marks chromatin at active transcription start sites. Nature, 622:173-179, 2023 Cited by PubMed: 37731000 DOI: 10.1038/s41586-023-06565-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation