8S97
C143W variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Summary for 8S97
| Entry DOI | 10.2210/pdb8s97/pdb |
| Descriptor | citrate synthase, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | citrate synthesis, tca cycle, c143w variant, cytosolic protein |
| Biological source | Mycobacterium tuberculosis H37Rv |
| Total number of polymer chains | 1 |
| Total formula weight | 41350.94 |
| Authors | Pathirage, R.,Ronning, D. (deposition date: 2023-03-27, release date: 2023-06-07, Last modification date: 2023-11-08) |
| Primary citation | Pathirage, R.,Favrot, L.,Petit, C.,Yamsek, M.,Singh, S.,Mallareddy, J.R.,Rana, S.,Natarajan, A.,Ronning, D.R. Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14:921-933, 2023 Cited by PubMed: 37252106DOI: 10.1039/d3md00058c PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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