8S72

Crystal structure of neutralizing Fab Eq4.Dp46-3D from equine antivenom bound to a consensus short chain three finger alpha-neurotoxin.

Summary for 8S72

• Entry DOI: 10.2210/pdb8s72/pdb
• Related: 8R4N
• Descriptor: Short neurotoxin 1, Heavy chain of Fab domain from antivenom neutralizing antibody Eq4.Dp46-3D., Light chain of Fab domain from antivenom neutralizing antibody Eq4.Dp46-3D., ... (4 entities in total)
• Functional Keywords: monoclonal antibody, antivenom, complex, short chain alpha-neurotoxin, antitoxin
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 108987.80

Authors

Ayres, F.,Wibmer, C.K. (deposition date: 2024-02-28, release date: 2025-09-10)

• Primary citation: Ayres, F.,Patel, R.,Casewell, N.,Wibmer, C.K.; A monoclonal antibody from horses that neutralizes long and short chain three finger neurotoxins; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.78 Å)