8S5Z

Cryo-EM structure of hydroxychloroquine-bound human SLC19A3 in inward-open state

This is a non-PDB format compatible entry.

Summary for 8S5Z

• Entry DOI: 10.2210/pdb8s5z/pdb
• EMDB information: 19753
• Descriptor: Nb3.3, Thiamine transporter 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: slc19a3, vitamin transporter, thiamine transporter, mfs fold, nanobody complex, membrane protein
• Biological source: Lama glama; More
• Total number of polymer chains: 2
• Total formula weight: 75450.47

Authors

Gabriel, F.,Loew, C. (deposition date: 2024-02-26, release date: 2024-10-02)

• Primary citation: Gabriel, F.,Loew, C.; Structural basis of substrate transport and drug recognition by the human thiamine transporter SLC19A3; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)