8S2T

Cryo-EM structure of cell-free synthesized Human beta-1 adrenergic receptor cotranslationally inserted into a lipidic nanodiscs

Summary for 8S2T

• Entry DOI: 10.2210/pdb8s2t/pdb
• EMDB information: 19683
• Descriptor: Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: signal transduction, gpcr, co-translational nanodisc insertion, g-protein, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 155673.97

Authors

Merino, F.,Koeck, Z.,Ermel, U.,Dahlhaus, P.,Doetsch, V.,Kubicek, J.,Frangakis, A.S.,Hilger, D.,Bernhard, F. (deposition date: 2024-02-19, release date: 2025-05-21)

• Primary citation: Merino, F.,Koeck, Z.,Ermel, U.,Dahlhaus, P.,Doetsch, V.,Frangakis, A.S.,Hilger, D.,Bernhard, F.; Cryo-EM structure of cell-free synthesized Human beta-1 adrenergic receptor cotranslationally inserted into a lipidic nanodiscs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)