8S1A

c-KIT kinase domain in complex with crenolanib

8S1A の概要

• エントリーDOI: 10.2210/pdb8s1a/pdb
• 分子名称: Mast/stem cell growth factor receptor Kit, 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine (3 entities in total)
• 機能のキーワード: stem cell factor receptor, inhibitor, gist, resistance, kit, crenolanib, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75275.94

構造登録者

Teuber, A.,Mueller, M.P.,Rauh, D. (登録日: 2024-02-15, 公開日: 2025-09-03)

• 主引用文献: Teuber, A.,Niggenaber, J.,Kleinboelting, S.B.,Landel, I.,Warmuth, J.,Busick, D.,Mueller, M.P.,Bauer, S.,Rauh, D.; c-KIT kinase domain in complex with crenolanib; To Be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)