8S18

c-KIT kinase domain in complex with S116836

This is a non-PDB format compatible entry.

Summary for 8S18

• Entry DOI: 10.2210/pdb8s18/pdb
• Descriptor: Mast/stem cell growth factor receptor Kit, 3-[2-[2-(cyclopropylamino)pyrimidin-5-yl]ethynyl]-~{N}-[3-imidazol-1-yl-5-(trifluoromethyl)phenyl]-4-methyl-benzamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: stem cell factor receptor, gist, kit, inhibitor, resistance, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 75429.29

Authors

Teuber, A.,Mueller, M.P.,Rauh, D. (deposition date: 2024-02-15, release date: 2025-09-03)

• Primary citation: Teuber, A.,Niggenaber, J.,Kleinboelting, S.B.,Landel, I.,Warmuth, J.,Busick, D.,Mueller, M.P.,Bauer, S.,Rauh, D.; c-KIT kinase domain in complex with S116836; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)