8RXG

Crystal structure of alpha-keto C-methyl transferase SgvM bound to SAM

Summary for 8RXG

• Entry DOI: 10.2210/pdb8rxg/pdb
• Descriptor: Methyltransferase, ZINC ION, 2-OXO-4-METHYLPENTANOIC ACID, ... (6 entities in total)
• Functional Keywords: s adenosylmethionine-dependent methyltransferases, biocatalysis, c-alkylation, transferase
• Biological source: Streptomyces griseoviridis
• Total number of polymer chains: 1
• Total formula weight: 37540.92

Authors

Gerhardt, S.,Andexer, J.N. (deposition date: 2024-02-07, release date: 2024-07-24)

• Primary citation: Sommer-Kamann, C.,Breiltgens, J.,Zou, Z.,Gerhardt, S.,Saleem-Batcha, R.,Kemper, F.,Einsle, O.,Andexer, J.N.,Muller, M.; Structures and Protein Engineering of the alpha-Keto Acid C-Methyltransferases SgvM and MrsA for Rational Substrate Transfer.; Chembiochem, :e202400258-e202400258, 2024; PubMed: 38887142; DOI: 10.1002/cbic.202400258

Experimental method

X-RAY DIFFRACTION (1.813 Å)