8RTB

Extended inner membrane complex (IMC) protomer structure (TrwM/VirB3-TrwK/VirB4-TrwI/VirB6-TrwG/VirB8-TrwE/VirB10) from the fully-assembled R388 type IV secretion system determined by cryo-EM.

8RTB の概要

• エントリーDOI: 10.2210/pdb8rtb/pdb
• EMDBエントリー: 19485
• 分子名称: TrwM protein, TrwK protein, TrwG protein, ... (5 entities in total)
• 機能のキーワード: type iv secretion system type 4 secretion system t4ss inner membrane complex imc imc-protomer extended imc r388 plasmid conjugation bacterial secretion secretion secretion system protein complex virb3 virb4 virb6 virb8 virb10 trwm trwk trwi trwg trwe, membrane protein
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 380800.38

構造登録者

Mace, K.,Waksman, G. (登録日: 2024-01-25, 公開日: 2024-06-19, 最終更新日: 2024-07-03)

• 主引用文献: Mace, K.,Waksman, G.; Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis.; Embo J., 2024; PubMed: 38886579; DOI: 10.1038/s44318-024-00135-z

実験手法

ELECTRON MICROSCOPY (3.83 Å)