8RT7
Conformation-B of the full-length outer membrane core complex (TrwH/VirB7, TrwF/VirB9, TrwE/VirB10CTD) from the fully-assembled R388 type IV secretion system determined by cryo-EM.
Summary for 8RT7
Entry DOI | 10.2210/pdb8rt7/pdb |
EMDB information | 19481 |
Descriptor | TrwE protein, TrwF protein, TrwH (3 entities in total) |
Functional Keywords | type iv secretion system type 4 secretion system t4ss omcc conformation-b core complex outer membrane complex r388 plasmid conjugation bacterial secretion secretion secretion system protein complex virb10 virb9 virb7 trwe trwf trwh, membrane protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 46 |
Total formula weight | 1226340.61 |
Authors | Mace, K.,Waksman, G. (deposition date: 2024-01-25, release date: 2024-06-19, Last modification date: 2024-08-14) |
Primary citation | Mace, K.,Waksman, G. Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 43:3287-3306, 2024 Cited by PubMed: 38886579DOI: 10.1038/s44318-024-00135-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.93 Å) |
Structure validation
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