8ROI
Human cohesin SMC3-HD(EQ)/RAD21-N complex - ADP-bound conformation
Summary for 8ROI
Entry DOI | 10.2210/pdb8roi/pdb |
Descriptor | Structural maintenance of chromosomes protein 3, Double-strand-break repair protein rad21 homolog, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | 3d genome organization, chromatin, cohesin, atpase activity, atpase cycle, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 65436.51 |
Authors | Vitoria Gomes, M.,Romier, C. (deposition date: 2024-01-11, release date: 2024-09-11, Last modification date: 2024-09-25) |
Primary citation | Vitoria Gomes, M.,Landwerlin, P.,Diebold-Durand, M.L.,Shaik, T.B.,Durand, A.,Troesch, E.,Weber, C.,Brillet, K.,Lemee, M.V.,Decroos, C.,Dulac, L.,Antony, P.,Watrin, E.,Ennifar, E.,Golzio, C.,Romier, C. The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains. Cell Rep, 43:114656-114656, 2024 Cited by PubMed: 39240714DOI: 10.1016/j.celrep.2024.114656 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
Download full validation report