8RO1

Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'')

This is a non-PDB format compatible entry.

Summary for 8RO1

• Entry DOI: 10.2210/pdb8ro1/pdb
• Related: 8RO0 8RO2 9FMD
• EMDB information: 19398
• Descriptor: U2 snRNA, Intron lariat RNA, TPR_REGION domain-containing protein, ... (43 entities in total)
• Functional Keywords: pre-mrna splicing, intron lariat spliceosome, gene expression, spliceosome, splicing
• Biological source: Caenorhabditis elegans; More
• Total number of polymer chains: 49
• Total formula weight: 2289684.59

Authors

Vorlaender, M.K.,Rothe, P.,Plaschka, C. (deposition date: 2024-01-11, release date: 2024-08-07, Last modification date: 2024-08-21)

• Primary citation: Vorlander, M.K.,Rothe, P.,Kleifeld, J.,Cormack, E.D.,Veleti, L.,Riabov-Bassat, D.,Fin, L.,Phillips, A.W.,Cochella, L.,Plaschka, C.; Mechanism for the initiation of spliceosome disassembly.; Nature, 632:443-450, 2024; PubMed: 38925148; DOI: 10.1038/s41586-024-07741-1

Experimental method

ELECTRON MICROSCOPY (3 Å)