8RNU
CryoEM structure of recombinant human Bri2 BRICHOS oligomers
Summary for 8RNU
Entry DOI | 10.2210/pdb8rnu/pdb |
EMDB information | 19395 |
Descriptor | Integral membrane protein 2B (1 entity in total) |
Functional Keywords | chaperone, anti-amyloid, dementia, bri2 |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 167399.82 |
Authors | |
Primary citation | Chen, G.,Wang, Y.,Zheng, Z.,Jiang, W.,Leppert, A.,Zhong, X.,Belorusova, A.,Siegal, G.,Jegerschold, C.,Koeck, P.J.B.,Abelein, A.,Hebert, H.,Knight, S.D.,Johansson, J. Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein Sci., 33:e5063-e5063, 2024 Cited by PubMed: 38864729DOI: 10.1002/pro.5063 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report