8RMJ

Drosophila Semaphorin 2b in complex with glycosaminoglycan mimic SOS

Summary for 8RMJ

• Entry DOI: 10.2210/pdb8rmj/pdb
• Related PRD ID: PRD_900013
• Descriptor: FI18622p1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: semaphorin, glycosaminoglycan, axon guidance, bridge model, signaling protein
• Biological source: Drosophila melanogaster (fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 81517.43

Authors

Nourisanami, F.,Sobol, M.,Rozbesky, D. (deposition date: 2024-01-08, release date: 2024-07-31)

• Primary citation: Nourisanami, F.,Sobol, M.,Li, Z.,Horvath, M.,Kowalska, K.,Kumar, A.,Vlasak, J.,Koupilova, N.,Luginbuhl, D.J.,Luo, L.,Rozbesky, D.; Molecular mechanisms of proteoglycan-mediated semaphorin signaling in axon guidance.; Proc.Natl.Acad.Sci.USA, 121:e2402755121-e2402755121, 2024; PubMed: 39042673; DOI: 10.1073/pnas.2402755121

Experimental method

X-RAY DIFFRACTION (2.79 Å)