8RHZ

Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer

Summary for 8RHZ

Entry DOI	10.2210/pdb8rhz/pdb
Related	8Q7E 8Q7H
EMDB information	18216 18217 18218 18220 18221 18222 18223 19179
Descriptor	Cullin-9, E3 ubiquitin-protein ligase RBX1, ZINC ION (3 entities in total)
Functional Keywords	cullin-ring rbr e3 ligase, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	588344.53
Authors	Hopf, L.V.M.,Horn-Ghetko, D.,Prabu, J.R.,Schulman, B.A. (deposition date: 2023-12-17, release date: 2024-04-17, Last modification date: 2024-04-24)
Primary citation	Horn-Ghetko, D.,Hopf, L.V.M.,Tripathi-Giesgen, I.,Du, J.,Kostrhon, S.,Vu, D.T.,Beier, V.,Steigenberger, B.,Prabu, J.R.,Stier, L.,Bruss, E.M.,Mann, M.,Xiong, Y.,Schulman, B.A. Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38605244 DOI: 10.1038/s41594-024-01257-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.37 Å)

Structure validation