8RHR
E.coli Peptide Deformylase with bound inhibitor BB4
Summary for 8RHR
Entry DOI | 10.2210/pdb8rhr/pdb |
Descriptor | Peptide deformylase, ZINC ION, 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ... (6 entities in total) |
Functional Keywords | peptide deformylase (ec 3.5.1.88), inhibitor, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 20135.51 |
Authors | Kirschner, H.,Stoll, R.,Hofmann, E. (deposition date: 2023-12-16, release date: 2024-04-17, Last modification date: 2024-05-08) |
Primary citation | Kirschner, H.,Heister, N.,Zouatom, M.,Zhou, T.,Hofmann, E.,Scherkenbeck, J.,Stoll, R. Toward More Selective Antibiotic Inhibitors: A Structural View of the Complexed Binding Pocket of E. coli Peptide Deformylase. J.Med.Chem., 67:6384-6396, 2024 Cited by PubMed: 38574272DOI: 10.1021/acs.jmedchem.3c02382 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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