8RH3
Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Gemcitabine
This is a non-PDB format compatible entry.
Summary for 8RH3
Entry DOI | 10.2210/pdb8rh3/pdb |
Descriptor | Nucleoside 2-deoxyribosyltransferase, (2~{R},3~{R})-4,4-bis(fluoranyl)-2-(hydroxymethyl)oxolan-3-ol (3 entities in total) |
Functional Keywords | ribosylated, holoprotein, transferase, gemcitabine |
Biological source | Chroococcidiopsis thermalis PCC 7203 |
Total number of polymer chains | 4 |
Total formula weight | 72126.03 |
Authors | Tang, P.,Harding, C.J.,Czekster, C.M. (deposition date: 2023-12-14, release date: 2024-02-21, Last modification date: 2024-03-20) |
Primary citation | Tang, P.,Harding, C.J.,Dickson, A.L.,da Silva, R.G.,Harrison, D.J.,Czekster, C.M. Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis, 14:3090-3102, 2024 Cited by PubMed: 38449528DOI: 10.1021/acscatal.3c06260 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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