8RH2
Trimeric HSV-2G gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules.
Summary for 8RH2
Entry DOI | 10.2210/pdb8rh2/pdb |
EMDB information | 19163 19164 19165 19166 |
Descriptor | Envelope glycoprotein B, HDIT102 Fab heavy chain, HDIT102 Fab light chain (3 entities in total) |
Functional Keywords | ectodomain, post-fusion, fab molecule, trimeric, viral protein |
Biological source | Human herpesvirus 2 strain G More |
Total number of polymer chains | 9 |
Total formula weight | 453277.17 |
Authors | Kalbermatter, D.,Seyfizadeh, N.,Imhof, T.,Ries, M.,Mueller, C.,Jenner, L.,Blumenschein, E.,Yendrzheyevskiy, A.,Moog, K.,Eckert, D.,Engel, R.,Diebolder, P.,Chami, M.,Krauss, J.,Schaller, T.,Arndt, M. (deposition date: 2023-12-14, release date: 2024-06-19) |
Primary citation | Seyfizadeh, N.,Kalbermatter, D.,Imhof, T.,Ries, M.,Muller, C.,Jenner, L.,Blumenschein, E.,Yendrzheyevskiy, A.,Grun, F.,Moog, K.,Eckert, D.,Engel, R.,Diebolder, P.,Chami, M.,Krauss, J.,Schaller, T.,Arndt, M. Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31:56-56, 2024 Cited by PubMed: 38807208DOI: 10.1186/s12929-024-01045-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.12 Å) |
Structure validation
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