8RCK

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.

8RCK の概要

• エントリーDOI: 10.2210/pdb8rck/pdb
• EMDBエントリー: 19053 19056
• 分子名称: Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Regulatory-associated protein of mTOR, ... (6 entities in total)
• 機能のキーワード: target of rapamycin, mtor, cancer-associated mutants, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 487515.85

構造登録者

Anandapadamanaban, M.,Hay, I.M.,Perisic, O.,Williams, R.L. (登録日: 2023-12-06, 公開日: 2024-09-11)

• 主引用文献: Anandapadamanaban, M.,Hay, I.M.,Perisic, O.,Williams, R.L.; CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.4 Å)