8RBX
Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex
This is a non-PDB format compatible entry.
Summary for 8RBX
Entry DOI | 10.2210/pdb8rbx/pdb |
EMDB information | 19038 |
Descriptor | UNK-UNK-UNK-UNK-UNK-UNK-UNK-UNK, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, ... (44 entities in total) |
Functional Keywords | integrator complex, pre-termination complex, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 46 |
Total formula weight | 2703211.22 |
Authors | Fianu, I.,Ochmann, M.,Walshe, J.L.,Cramer, P. (deposition date: 2023-12-05, release date: 2024-02-07, Last modification date: 2024-05-15) |
Primary citation | Fianu, I.,Ochmann, M.,Walshe, J.L.,Dybkov, O.,Cruz, J.N.,Urlaub, H.,Cramer, P. Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629:219-227, 2024 Cited by PubMed: 38570683DOI: 10.1038/s41586-024-07269-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
Download full validation report