8RAX

The crystal structure of DNA-bound human MutSbeta (MSH2_G674D/MSH3) in the canonical mismatch bound conformation, nucleotide free

8RAX の概要

• エントリーDOI: 10.2210/pdb8rax/pdb
• 分子名称: DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, DNA (5'-D(P*AP*TP*CP*TP*GP*AP*AP*GP*CP*CP*GP*AP*TP*CP*GP*AP*TP*G)-3'), ... (5 entities in total)
• 機能のキーワード: dna binding, dna repair, dna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 223925.08

構造登録者

Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P. (登録日: 2023-12-01, 公開日: 2025-06-11, 最終更新日: 2025-07-09)

• 主引用文献: Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P.; The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3; To Be Published,

実験手法

X-RAY DIFFRACTION (3.162 Å)