8R8T

Cryo-EM structure of the inward-facing ethanolamine-bound FLVCR1

Summary for 8R8T

• Entry DOI: 10.2210/pdb8r8t/pdb
• Related: 8QCS
• EMDB information: 19009
• Descriptor: Heme transporter FLVCR1, ETHANOLAMINE (2 entities in total)
• Functional Keywords: mfs, ethanolamine transport, human transporter, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 60957.40

Authors

Weng, T.-H.,Wu, D.,Safarian, S. (deposition date: 2023-11-29, release date: 2024-04-17, Last modification date: 2024-06-19)

• Primary citation: Ri, K.,Weng, T.H.,Claveras Cabezudo, A.,Josting, W.,Zhang, Y.,Bazzone, A.,Leong, N.C.P.,Welsch, S.,Doty, R.T.,Gursu, G.,Lim, T.J.Y.,Schmidt, S.L.,Abkowitz, J.L.,Hummer, G.,Wu, D.,Nguyen, L.N.,Safarian, S.; Molecular mechanism of choline and ethanolamine transport in humans.; Nature, 630:501-508, 2024; PubMed: 38778100; DOI: 10.1038/s41586-024-07444-7

Experimental method

ELECTRON MICROSCOPY (2.9 Å)