8R47

AL amyloid fibril from the FOR010 light chain

Summary for 8R47

Entry DOI	10.2210/pdb8r47/pdb
EMDB information	18881
Descriptor	lambda 3 immunoglobulin light chain fragment, residues 4-116 (1 entity in total)
Functional Keywords	amyloid fibril, al amyloid, protein fibril
Biological source	Homo sapiens
Total number of polymer chains	6
Total formula weight	72380.02
Authors	Pfeiffer, P.B.,Banerjee, S.,Schmidt, M.,Faendrich, M. (deposition date: 2023-11-13, release date: 2024-06-26)
Primary citation	Karimi-Farsijani, S.,Pfeiffer, P.B.,Banerjee, S.,Baur, J.,Kuhn, L.,Kupfer, N.,Hegenbart, U.,Schonland, S.O.,Wiese, S.,Haupt, C.,Schmidt, M.,Fandrich, M. Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. Nat Commun, 15:5121-5121, 2024 Cited by PubMed: 38879609 DOI: 10.1038/s41467-024-49520-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.25 Å)

Structure validation