8R2J

X-ray crystallographic structure of SwaQ2 in complex with NADP+ and doxorubicin

8R2J の概要

• エントリーDOI: 10.2210/pdb8r2j/pdb
• 分子名称: NmrA family transcriptional regulator, DOXORUBICIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: polyketide, antibiotic, biosynthesis, biosynthetic protein
• 由来する生物種: Streptomyces swartbergensis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66537.02

構造登録者

Schnell, R.,Schneider, G. (登録日: 2023-11-06, 公開日: 2024-08-07)

• 主引用文献: Wandi, B.N.,Dinis, P.,Siitonen, V.,Schneider, G.,Schnell, R.,Metsa-Ketele, M.; Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation; Acs Catalysis, 2024; DOI: 10.1021/acscatal.4c02623

実験手法

X-RAY DIFFRACTION (2.4 Å)