8R1I

Human Carbonic Anhydrase II (hCAII) in complex with (R)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide

8R1I の概要

• エントリーDOI: 10.2210/pdb8r1i/pdb
• 分子名称: Carbonic anhydrase 2, (R)-N-(3-INDOL-1-YL-2-METHYL-PROPYL)-4-SULFAMOYL-BENZAMIDE, ZINC ION, ... (4 entities in total)
• 機能のキーワード: inhibitor, carbonic anhydrase, co-crystallization, complex, zn2+ coordination site, metal binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30243.45

構造登録者

Kotschy, J.,Gasper, R.,Linser, R. (登録日: 2023-11-02, 公開日: 2023-12-06, 最終更新日: 2024-01-31)

• 主引用文献: Kotschy, J.,Soldner, B.,Singh, H.,Vasa, S.K.,Linser, R.; Microsecond Timescale Conformational Dynamics of a Small-Molecule Ligand within the Active Site of a Protein.; Angew.Chem.Int.Ed.Engl., 63:e202313947-e202313947, 2024; PubMed: 37974542; DOI: 10.1002/anie.202313947

実験手法

X-RAY DIFFRACTION (1.46 Å)