8R0A
Cryo-EM structure of the cross-exon pre-B+5'ss complex
This is a non-PDB format compatible entry.
Summary for 8R0A
Entry DOI | 10.2210/pdb8r0a/pdb |
EMDB information | 18788 |
Descriptor | U5 snRNA, pre-mRNA, 5'ss oligo, ... (48 entities in total) |
Functional Keywords | spliceosome, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 62 |
Total formula weight | 2806145.12 |
Authors | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-10-31, release date: 2024-05-22, Last modification date: 2024-07-10) |
Primary citation | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R. Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630:1012-1019, 2024 Cited by PubMed: 38778104DOI: 10.1038/s41586-024-07458-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.8 Å) |
Structure validation
Download full validation report