8R02

Crystal structure of the retromer complex VPS29/VPS35 with the ligand bis-1,3-phenyl guanylhydrazone, 2a

8R02 の概要

• エントリーDOI: 10.2210/pdb8r02/pdb
• 分子名称: Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, Bis-1,3-phenyl guanylhydrazon, ... (4 entities in total)
• 機能のキーワード: complex, transport, recycling, ligand, protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 112592.76

構造登録者

Milani, M.,Fagnani, E. (登録日: 2023-10-30, 公開日: 2024-03-27)

• 主引用文献: Fagnani, E.,Boni, F.,Seneci, P.,Gornati, D.,Muzio, L.,Mastrangelo, E.,Milani, M.; Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface.; Comput Struct Biotechnol J, 23:1088-1093, 2024; PubMed: 38487369; DOI: 10.1016/j.csbj.2024.02.026

実験手法

X-RAY DIFFRACTION (2.5 Å)