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8QWF

ReChb - crRNA - target dsDNA complex in the presence of collateral dsDNA

Summary for 8QWF
Entry DOI10.2210/pdb8qwf/pdb
EMDB information18691 18692 18693 18694
DescriptorReChb, crRNA, non target DNA, ... (5 entities in total)
Functional Keywordscas, biosynthetic protein, cryo-em, ancestral sequence reconstruction, biotechnology, dna, rna
Biological sourcesynthetic construct
More
Total number of polymer chains4
Total formula weight185803.87
Authors
Lopez-Alonso, J.P.,Ubarretxena-Belandia, I.,Tascon, I. (deposition date: 2023-10-19, release date: 2024-10-02)
Primary citationJabalera, Y.,Tascon, I.,Samperio, S.,Lopez-Alonso, J.P.,Gonzalez-Lopez, M.,Aransay, A.M.,Abascal-Palacios, G.,Beisel, C.L.,Ubarretxena-Belandia, I.,Jimenez-Perez, R.
A resurrected ancestor of Cas12a expands target access and substrate 2 recognition for nucleic-acid editing and detection
Nature Biotechnology, 2024
Experimental method
ELECTRON MICROSCOPY (3.08 Å)
Structure validation

225946

건을2024-10-09부터공개중

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