8QSQ

Locally refined SARS-CoV-2 BA-2.86 Spike receptor binding domain (RBD) complexed with angiotensin converting enzyme 2 (ACE2)

This is a non-PDB format compatible entry.

Summary for 8QSQ

• Entry DOI: 10.2210/pdb8qsq/pdb
• EMDB information: 18639
• Descriptor: Spike protein S2', Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: viral protein, immune system, sars-cov-2, ace2, rbd, spike, glycoprotein, ba.2.86, angiotensin converting enzyme 2, receptor, coronavirus-2
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 93468.86

Authors

Ren, J.,Stuart, D.I.,Duyvesteyn, H.M.E. (deposition date: 2023-10-11, release date: 2024-05-08, Last modification date: 2024-06-05)

• Primary citation: Liu, C.,Zhou, D.,Dijokaite-Guraliuc, A.,Supasa, P.,Duyvesteyn, H.M.E.,Ginn, H.M.,Selvaraj, M.,Mentzer, A.J.,Das, R.,de Silva, T.I.,Ritter, T.G.,Plowright, M.,Newman, T.A.H.,Stafford, L.,Kronsteiner, B.,Temperton, N.,Lui, Y.,Fellermeyer, M.,Goulder, P.,Klenerman, P.,Dunachie, S.J.,Barton, M.I.,Kutuzov, M.A.,Dushek, O.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.; Cell Rep Med, 5:101553-101553, 2024; PubMed: 38723626; DOI: 10.1016/j.xcrm.2024.101553

Experimental method

ELECTRON MICROSCOPY (3.7 Å)