8QQR

Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, super-compressed

Summary for 8QQR

• Entry DOI: 10.2210/pdb8qqr/pdb
• Related: 8PW3
• EMDB information: 18602
• Descriptor: Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5',3'-TETRAPHOSPHATE, ... (4 entities in total)
• Functional Keywords: octamer, atp+ppgpp complex, purine metabolism, impdh, oxidoreductase
• Biological source: Mycolicibacterium smegmatis MC2 155
• Total number of polymer chains: 8
• Total formula weight: 436383.51

Authors

Bulvas, O.,Kouba, T.,Pichova, I. (deposition date: 2023-10-06, release date: 2024-08-14, Last modification date: 2024-08-21)

• Primary citation: Bulvas, O.,Knejzlik, Z.,Sys, J.,Filimonenko, A.,Cizkova, M.,Clarova, K.,Rejman, D.,Kouba, T.,Pichova, I.; Deciphering the allosteric regulation of mycobacterial inosine-5'-monophosphate dehydrogenase.; Nat Commun, 15:6673-6673, 2024; PubMed: 39107302; DOI: 10.1038/s41467-024-50933-6

Experimental method

ELECTRON MICROSCOPY (2.73 Å)