8QPE

Cryo-EM Structure of Pre-B-like Complex (core part)

This is a non-PDB format compatible entry.

Summary for 8QPE

• Entry DOI: 10.2210/pdb8qpe/pdb
• EMDB information: 18548
• Descriptor: U4 snRNA, Ubiquitin carboxyl-terminal hydrolase 39, WW domain-binding protein 4, ... (21 entities in total)
• Functional Keywords: spliceosome, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 20
• Total formula weight: 1237154.62

Authors

Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-10-01, release date: 2024-05-22, Last modification date: 2024-07-10)

• Primary citation: Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Structural insights into the cross-exon to cross-intron spliceosome switch.; Nature, 630:1012-1019, 2024; PubMed: 38778104; DOI: 10.1038/s41586-024-07458-1

Experimental method

ELECTRON MICROSCOPY (3.1 Å)