8QMZ

Soluble epoxide hydrolase in complex with RK4

8QMZ の概要

• エントリーDOI: 10.2210/pdb8qmz/pdb
• 分子名称: Bifunctional epoxide hydrolase 2, (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: complex, structural genomics, structural genomics consortium, sgc, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 170667.07

構造登録者

Kumar, A.,Zhu, F.,Ehrler, J.M.H.,Li, F.,Empel, C.,Xu, Y.,Atodiresei, I.,Koenigs, R.M.,Proschak, E.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2023-09-25, 公開日: 2024-02-14)

• 主引用文献: Li, F.,Zhu, W.F.,Empel, C.,Datsenko, O.,Kumar, A.,Xu, Y.,Ehrler, J.H.M.,Atodiresei, I.,Knapp, S.,Mykhailiuk, P.K.,Proschak, E.,Koenigs, R.M.; Photosensitization enables Pauson-Khand-type reactions with nitrenes.; Science, 383:498-503, 2024; PubMed: 38301027; DOI: 10.1126/science.adm8095

実験手法

X-RAY DIFFRACTION (1.47 Å)