8QLP
CryoEM structure of the RNA/DNA bound SPARTA (BabAgo/TIR-APAZ) tetrameric complex
Summary for 8QLP
Entry DOI | 10.2210/pdb8qlp/pdb |
EMDB information | 18487 |
Descriptor | Toll/interleukin-1 receptor domain-containing protein, Short prokaryotic Argonaute, RNA (5'-R(*AP*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... (5 entities in total) |
Functional Keywords | prokaryotic argonaute, tir domain, rna binding protein, dna binding protein, immune system, oligomerization, nadase activity |
Biological source | Bacillales bacterium More |
Total number of polymer chains | 16 |
Total formula weight | 501259.23 |
Authors | Finocchio, G.,Koopal, B.,Potocnik, A.,Heijstek, C.,Jinek, M.,Swarts, D. (deposition date: 2023-09-20, release date: 2024-01-31, Last modification date: 2024-03-06) |
Primary citation | Finocchio, G.,Koopal, B.,Potocnik, A.,Heijstek, C.,Westphal, A.H.,Jinek, M.,Swarts, D.C. Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res., 52:2012-2029, 2024 Cited by PubMed: 38224450DOI: 10.1093/nar/gkad1248 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.14 Å) |
Structure validation
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