8QKS

Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to R5.034

Summary for 8QKS

• Entry DOI: 10.2210/pdb8qks/pdb
• Descriptor: Reticulocyte-binding protein-like protein 5, Immunoglobulin lambda variable 1-36, R5034HV (3 entities in total)
• Functional Keywords: malaria rh5 antibody clonotype, immune system
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 24
• Total formula weight: 495233.11

Authors

Wright, N.D.,Barrett, J.R.,Bradshaw, W.J.,Paterson, N.G.,MacLean, E.M.,Ferreira, L.,McHugh, K.,Von Delft, F.,Koekemoer, L.,Draper, S.J. (deposition date: 2023-09-16, release date: 2024-07-31, Last modification date: 2024-09-04)

• Primary citation: Barrett, J.R.,Pipini, D.,Wright, N.D.,Cooper, A.J.R.,Gorini, G.,Quinkert, D.,Lias, A.M.,Davies, H.,Rigby, C.A.,Aleshnick, M.,Williams, B.G.,Bradshaw, W.J.,Paterson, N.G.,Martinson, T.,Kirtley, P.,Picard, L.,Wiggins, C.D.,Donnellan, F.R.,King, L.D.W.,Wang, L.T.,Popplewell, J.F.,Silk, S.E.,de Ruiter Swain, J.,Skinner, K.,Kotraiah, V.,Noe, A.R.,MacGill, R.S.,King, C.R.,Birkett, A.J.,Soisson, L.A.,Minassian, A.M.,Lauffenburger, D.A.,Miura, K.,Long, C.A.,Wilder, B.K.,Koekemoer, L.,Tan, J.,Nielsen, C.M.,McHugh, K.,Draper, S.J.; Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.; Cell, 2024; PubMed: 39059380; DOI: 10.1016/j.cell.2024.06.015

Experimental method

X-RAY DIFFRACTION (3.994 Å)