8QIC
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors
Summary for 8QIC
Entry DOI | 10.2210/pdb8qic/pdb |
Descriptor | Threonine--tRNA ligase, 2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid, GLYCEROL, ... (5 entities in total) |
Functional Keywords | threonyl trna-synthetase, malaria, plasmodium falciparum, salicylic acid, ligase |
Biological source | Escherichia coli O8 |
Total number of polymer chains | 2 |
Total formula weight | 94402.00 |
Authors | |
Primary citation | Bobrovs, R.,Bolsakova, J.,Buitrago, J.A.R.,Varaceva, L.,Skvorcova, M.,Kanepe, I.,Rudnickiha, A.,Parisini, E.,Jirgensons, A. Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors. Plos One, 19:e0296995-e0296995, 2024 Cited by PubMed: 38558084DOI: 10.1371/journal.pone.0296995 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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