8QHE

Crystal structure IR-09

8QHE の概要

• エントリーDOI: 10.2210/pdb8qhe/pdb
• 分子名称: 6-phosphogluconate dehydrogenase NADP-binding domain-containing protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ~{N}-methylcyclohexanamine, ... (5 entities in total)
• 機能のキーワード: reductase, biosynthetic protein
• 由来する生物種: Aspergillus lentulus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33068.60

構造登録者

Levy, C.W. (登録日: 2023-09-07, 公開日: 2023-10-11, 最終更新日: 2023-10-25)

• 主引用文献: Casamajo, A.R.,Yu, Y.,Schnepel, C.,Morrill, C.,Barker, R.,Levy, C.W.,Finnigan, J.,Spelling, V.,Westerlund, K.,Petchey, M.,Sheppard, R.J.,Lewis, R.J.,Falcioni, F.,Hayes, M.A.,Turner, N.J.; Biocatalysis in Drug Design: Engineered Reductive Aminases (RedAms) Are Used to Access Chiral Building Blocks with Multiple Stereocenters.; J.Am.Chem.Soc., 145:22041-22046, 2023; PubMed: 37782882; DOI: 10.1021/jacs.3c07010

実験手法

X-RAY DIFFRACTION (1.6 Å)