8QFY
Crystal structure of high affinity TCR in complex with pHLA harbouring bacterial peptide
This is a non-PDB format compatible entry.
Summary for 8QFY
Entry DOI | 10.2210/pdb8qfy/pdb |
Descriptor | HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, Peptide from inhA, ... (7 entities in total) |
Functional Keywords | t-cell receptor, hla-e, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 10 |
Total formula weight | 189031.57 |
Authors | Pengelly, R.J.,Robinson, R.A. (deposition date: 2023-09-05, release date: 2024-05-15, Last modification date: 2024-10-16) |
Primary citation | Paterson, R.L.,La Manna, M.P.,Arena De Souza, V.,Walker, A.,Gibbs-Howe, D.,Kulkarni, R.,Fergusson, J.R.,Mulakkal, N.C.,Monteiro, M.,Bunjobpol, W.,Dembek, M.,Martin-Urdiroz, M.,Grant, T.,Barber, C.,Garay-Baquero, D.J.,Tezera, L.B.,Lowne, D.,Britton-Rivet, C.,Pengelly, R.,Chepisiuk, N.,Singh, P.K.,Woon, A.P.,Powlesland, A.S.,McCully, M.L.,Caccamo, N.,Salio, M.,Badami, G.D.,Dorrell, L.,Knox, A.,Robinson, R.,Elkington, P.,Dieli, F.,Lepore, M.,Leonard, S.,Godinho, L.F. An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 121:e2318003121-e2318003121, 2024 Cited by PubMed: 38691588DOI: 10.1073/pnas.2318003121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
Download full validation report